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diabzi  (MedChemExpress)


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    Structured Review

    MedChemExpress diabzi
    Characterization of DI/Ce6 <t>and</t> <t>DI/Ce6@STF.</t> (A, B) Representative electron microscopy images of DI/Ce6 and DI/Ce6@STF, respectively (scale bar: 100 nm); (C) Zeta potential of DI/Ce6 and DI/Ce6@STF; (D, E) Hydrodynamic particle size distributions of DI/Ce6 and DI/Ce6@STF measured by dynamic light scattering; (F) Particle size stability of DI/Ce6 and DI/Ce6@STF in PBS over 7 days; (G, H) Release Curves of <t>DIABZI</t> and STF-31 in DI/Ce6@STF; (I) Comparison of HPLC chromatograms for DI/Ce6@STF nanoparticles and free drug.
    Diabzi, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 21 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/sting+agonist/pmc13067122-183-2-10?v=MedChemExpress
    Average 94 stars, based on 21 article reviews
    diabzi - by Bioz Stars, 2026-07
    94/100 stars

    Images

    1) Product Images from "A photodynamically activated nanoplatform relieves glucose-driven immunosuppression to potentiate STING immunotherapy in triple-negative breast cancer"

    Article Title: A photodynamically activated nanoplatform relieves glucose-driven immunosuppression to potentiate STING immunotherapy in triple-negative breast cancer

    Journal: Materials Today Bio

    doi: 10.1016/j.mtbio.2026.103071

    Characterization of DI/Ce6 and DI/Ce6@STF. (A, B) Representative electron microscopy images of DI/Ce6 and DI/Ce6@STF, respectively (scale bar: 100 nm); (C) Zeta potential of DI/Ce6 and DI/Ce6@STF; (D, E) Hydrodynamic particle size distributions of DI/Ce6 and DI/Ce6@STF measured by dynamic light scattering; (F) Particle size stability of DI/Ce6 and DI/Ce6@STF in PBS over 7 days; (G, H) Release Curves of DIABZI and STF-31 in DI/Ce6@STF; (I) Comparison of HPLC chromatograms for DI/Ce6@STF nanoparticles and free drug.
    Figure Legend Snippet: Characterization of DI/Ce6 and DI/Ce6@STF. (A, B) Representative electron microscopy images of DI/Ce6 and DI/Ce6@STF, respectively (scale bar: 100 nm); (C) Zeta potential of DI/Ce6 and DI/Ce6@STF; (D, E) Hydrodynamic particle size distributions of DI/Ce6 and DI/Ce6@STF measured by dynamic light scattering; (F) Particle size stability of DI/Ce6 and DI/Ce6@STF in PBS over 7 days; (G, H) Release Curves of DIABZI and STF-31 in DI/Ce6@STF; (I) Comparison of HPLC chromatograms for DI/Ce6@STF nanoparticles and free drug.

    Techniques Used: Electron Microscopy, Zeta Potential Analyzer, Comparison



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    Characterization of DI/Ce6 <t>and</t> <t>DI/Ce6@STF.</t> (A, B) Representative electron microscopy images of DI/Ce6 and DI/Ce6@STF, respectively (scale bar: 100 nm); (C) Zeta potential of DI/Ce6 and DI/Ce6@STF; (D, E) Hydrodynamic particle size distributions of DI/Ce6 and DI/Ce6@STF measured by dynamic light scattering; (F) Particle size stability of DI/Ce6 and DI/Ce6@STF in PBS over 7 days; (G, H) Release Curves of <t>DIABZI</t> and STF-31 in DI/Ce6@STF; (I) Comparison of HPLC chromatograms for DI/Ce6@STF nanoparticles and free drug.
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    Characterization of DI/Ce6 <t>and</t> <t>DI/Ce6@STF.</t> (A, B) Representative electron microscopy images of DI/Ce6 and DI/Ce6@STF, respectively (scale bar: 100 nm); (C) Zeta potential of DI/Ce6 and DI/Ce6@STF; (D, E) Hydrodynamic particle size distributions of DI/Ce6 and DI/Ce6@STF measured by dynamic light scattering; (F) Particle size stability of DI/Ce6 and DI/Ce6@STF in PBS over 7 days; (G, H) Release Curves of <t>DIABZI</t> and STF-31 in DI/Ce6@STF; (I) Comparison of HPLC chromatograms for DI/Ce6@STF nanoparticles and free drug.
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    Characterization of DI/Ce6 <t>and</t> <t>DI/Ce6@STF.</t> (A, B) Representative electron microscopy images of DI/Ce6 and DI/Ce6@STF, respectively (scale bar: 100 nm); (C) Zeta potential of DI/Ce6 and DI/Ce6@STF; (D, E) Hydrodynamic particle size distributions of DI/Ce6 and DI/Ce6@STF measured by dynamic light scattering; (F) Particle size stability of DI/Ce6 and DI/Ce6@STF in PBS over 7 days; (G, H) Release Curves of <t>DIABZI</t> and STF-31 in DI/Ce6@STF; (I) Comparison of HPLC chromatograms for DI/Ce6@STF nanoparticles and free drug.
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    Characterization of DI/Ce6 <t>and</t> <t>DI/Ce6@STF.</t> (A, B) Representative electron microscopy images of DI/Ce6 and DI/Ce6@STF, respectively (scale bar: 100 nm); (C) Zeta potential of DI/Ce6 and DI/Ce6@STF; (D, E) Hydrodynamic particle size distributions of DI/Ce6 and DI/Ce6@STF measured by dynamic light scattering; (F) Particle size stability of DI/Ce6 and DI/Ce6@STF in PBS over 7 days; (G, H) Release Curves of <t>DIABZI</t> and STF-31 in DI/Ce6@STF; (I) Comparison of HPLC chromatograms for DI/Ce6@STF nanoparticles and free drug.
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    Image Search Results


    Characterization of DI/Ce6 and DI/Ce6@STF. (A, B) Representative electron microscopy images of DI/Ce6 and DI/Ce6@STF, respectively (scale bar: 100 nm); (C) Zeta potential of DI/Ce6 and DI/Ce6@STF; (D, E) Hydrodynamic particle size distributions of DI/Ce6 and DI/Ce6@STF measured by dynamic light scattering; (F) Particle size stability of DI/Ce6 and DI/Ce6@STF in PBS over 7 days; (G, H) Release Curves of DIABZI and STF-31 in DI/Ce6@STF; (I) Comparison of HPLC chromatograms for DI/Ce6@STF nanoparticles and free drug.

    Journal: Materials Today Bio

    Article Title: A photodynamically activated nanoplatform relieves glucose-driven immunosuppression to potentiate STING immunotherapy in triple-negative breast cancer

    doi: 10.1016/j.mtbio.2026.103071

    Figure Lengend Snippet: Characterization of DI/Ce6 and DI/Ce6@STF. (A, B) Representative electron microscopy images of DI/Ce6 and DI/Ce6@STF, respectively (scale bar: 100 nm); (C) Zeta potential of DI/Ce6 and DI/Ce6@STF; (D, E) Hydrodynamic particle size distributions of DI/Ce6 and DI/Ce6@STF measured by dynamic light scattering; (F) Particle size stability of DI/Ce6 and DI/Ce6@STF in PBS over 7 days; (G, H) Release Curves of DIABZI and STF-31 in DI/Ce6@STF; (I) Comparison of HPLC chromatograms for DI/Ce6@STF nanoparticles and free drug.

    Article Snippet: STF-31 (HY-18728), DIABZI (HY-112921A) and Ce6(HY-13594) were all purchased from MedChemExpress (Shanghai, China).

    Techniques: Electron Microscopy, Zeta Potential Analyzer, Comparison

    Chemical structures of drugs interacting with the cGAS/STING pathway. The various agonists to the cGAS/STING pathway investigated in the context of solid cancers with (A) cyclic dinucleotide (CDN)-based agonists as analogues of the natural STING agonist 2’3’-cGAMP; (B) Non-CDNs, small molecule-based STING agonists which are resistant to cleavage by phosphodiesterase enzyme ENPP1; and (C) metal-based STING agonists which are thought to interact synergistically with widely available metal-based chemotherapeutic agents such as the platins to augment therapeutic effects. Figure created in Chemdraw.

    Journal: Frontiers in Oncology

    Article Title: STING agonism in brain tumours: mechanisms, challenges, and therapeutic advances

    doi: 10.3389/fonc.2026.1679361

    Figure Lengend Snippet: Chemical structures of drugs interacting with the cGAS/STING pathway. The various agonists to the cGAS/STING pathway investigated in the context of solid cancers with (A) cyclic dinucleotide (CDN)-based agonists as analogues of the natural STING agonist 2’3’-cGAMP; (B) Non-CDNs, small molecule-based STING agonists which are resistant to cleavage by phosphodiesterase enzyme ENPP1; and (C) metal-based STING agonists which are thought to interact synergistically with widely available metal-based chemotherapeutic agents such as the platins to augment therapeutic effects. Figure created in Chemdraw.

    Article Snippet: NCT05549804 , A Study of Intratumoural KL340399 in Patients with Advanced Solid Tumours , Single-centre, open-label, dose-escalation n=30 , Advanced solid tumours , Non-cyclic dinucleotide STING agonist , intratumoural , Sichuan Kelun Pharmaceutical Research Institute Co., Ltd. , 1 (active).

    Techniques: Analogues